Possible association between subclinical hypothyroidism and age at menopause in Colombian women.

OBJECTIVE: To evaluate the association between subclinical hypothyroidism with early menopause, premature menopause, and last menstrual bleeding before the natural age of menopause. METHODS: This was a cross-sectional study conducted in 643 postmenopausal women aged 40-69 years. Groups were formed according to last menstrual episode: ≥45 [Natural age at menopause], 40-44 and [Early menopause], <40 [Premature menopause], and <45 [last menstrual episode before the natural age of menopause]. The Zulewski scale was applied to identify manifestations related to hypothyroidism and subclinical hypothyroidism, diagnosed with a serum TSH > 4.5 µIU/mL plus T4-free between 0.7 and 1.9 ng/dL. RESULTS: It was found that 24.4% had the last menstrual episode before the natural age of menopause, 18.6% had early menopause, and 5.7% had premature menopause. Subclinical hypothyroidism was diagnosed in 4.5% of patients. Among women with subclinical hypothyroidism, there was a higher frequency of early menopause, premature menopause, and last menstrual episode before the natural age of menopause, than in women without subclinical hypothyroidism (p < 0.05). Paresthesia (50%) and dry skin (40.7%) were the most reported hypothyroidism-related manifestations. Early menopause, premature menopause, and last menstrual episode before the natural age of menopause were associated with subclinical hypothyroidism, OR: 3.37 [95% CI: 1.40-8.10], OR: 4.31 [95% CI: 1.24-14.97], and OR: 3.57 [95% CI: 1.57-8.10], respectively. CONCLUSIONS: The last menstrual episode before the natural age of menopause, early menopause, and premature menopause were significantly associated with a higher chance of subclinical hypothyroidism.

Clinical considerations for sarcopenia in older Colombian Afro-descendant and mestizo women.

OBJECTIVES: To identify the frequencies of clinical suspicion of sarcopenia (CSS) and probable sarcopenia (PS) and their association with ethnic groups. METHODS: This cross-sectional study categorized 700 women into Afro-descendant and mestizo ethnic groups. Calf circumference, muscle strength, and gait speed were measured. CSS was assessed using a sarcopenia risk scale and the measurement of calf circumference; the muscle strength of the dominant hand was used to establish PS. Unadjusted logistic regressions assessed associations between CSS/PS and ethnicity. Two adjusted logistic regression models included relevant covariates. RESULTS: CSS and PS were identified in 10.4% to 20.7% and 7.8% to 14.1% of study participants, respectively. Compared with mestizos, Afro-descendants had a more favorable sarcopenia risk score, greater calf circumference, and greater muscle strength and were associated with a lower risk for CSS (odds ratio [OR]: 0.13, 95% confidence interval [CI]: 0.06-0.28 and OR: 0.12, 95% CI: 0.07-0.21) and PS (OR: 0.12, 95% CI: 0.05-0.30 and OR: 0.11, 95% CI: 0.06-0.21). CONCLUSION: Compared with mestizos, CSS and PS were less frequent among Afro-descendants, who had 87% to 88% lower probability of CSS and 88% to 89% lower probability of PS.

Positive maternal mental health in pregnant women and its association with obstetric and psychosocial factors.

OBJECTIVE: To estimate the frequency of Positive Maternal Mental Health (PMMH) interpretation levels in pregnant women who attended prenatal consultation and to identify their association with obstetric and psychosocial factors. METHODS: A cross-sectional study that included pregnant women who attended prenatal care at 12 or more weeks of gestation. The following scales were applied: Positive Mental Health Questionnaire (PMHQ), Goldberg Anxiety and Depression Scale, and Jong Gierveld Loneliness Scale. RESULTS: 702 pregnant women were evaluated; 634 (90.3%) had flourishing PMMH, and 68 (9.7%) had non-flourishing PMMH. Among the latter, all were at an intermediate level, and none were languishing. Flourishing PMMH was more frequent in adults (91.2%) compared to adolescents (75.0%) and in women with higher education (93.0%) than in those with basic education (83.9%). The PMHQ factors and global score correlated positively with maternal age and negatively with anxiety, depression, emotional, social, and general loneliness. Associated with a higher frequency of non-flourishing PMMH were general loneliness OR:6.32[CI95%:3.38-11.82], social loneliness OR:5.98[CI95%:3.42-10.42], adolescence OR:3.47[CI95%:1.61-7.45], emotional loneliness OR:3.12[1.83-5.32], anxiety OR:2.14[CI95%:1.27-3.60], and depression OR:1.88[CI95%:1.09-3.25]. Less frequently: work occupation outside the home OR:0.41[CI95%:0.24-0.68], technical/technological studies OR:0.22[CI95%:0.08-0.60] and university OR:0.27[CI95%:0.10-0.71]. Preconception consultation, desired pregnancy, cesarean section, and fetal or neonatal death were not associated. In the adjusted model: general loneliness OR:3.02[CI95%:1.10-8.31], social loneliness OR:2.82[CI95%:1.38-5.79] and anxiety OR:1.93[CI95%:1.02-3.67], retained statistical significance. CONCLUSION: Nine out of ten pregnant women had flourishing PMMH, and none had languishing PMMH. None of the obstetric factors were associated with non-flourishing PMMH but with general loneliness, social loneliness, and anxiety.

Clinical suspicion of sarcopenic obesity and probable sarcopenic obesity in Colombian women with a history of surgical menopause: a cross-sectional study.

OBJECTIVES: To identify the frequency of clinical suspicion of sarcopenic obesity (CSSO) and probable sarcopenic obesity (PSO) and to estimate the association between them and surgical menopause. METHODS: A cross-sectional study carried out in women residing in Colombia, ages 60 to 75 years. Body mass index, the SARC-F scale, SARC-CalF < 31, and SARC-CalF <33 versions adding the calf circumference measurement in the last two were used to identify CSSO. Muscle strength measurement was added to the above measures to establish PSO. Surgical menopause was defined in women who underwent bilateral oophorectomy simultaneously with hysterectomy before natural menopause. Adjusted and unadjusted logistic regression were performed between CSSO or PSO with surgical menopause, bilateral oophorectomy after natural menopause, and abdominal hysterectomy with ovarian preservation. All participants provided informed consent. P < 0.05 was statistically significant. RESULTS: Seven hundred women 67.0 ±â€Š4.8 years old were included; 23.7% were obese, 68.1% had reduced muscle strength, and 4.2% had surgical menopause. CSSO was found in 3.0% with SARC-F and with SARC-CalF < 31; whereas 2.0% were found with SARC-CalF <33. PSO was found in 2.4%, 1.5%, and 2.2% with SARC-F, SARC-CalF <31, and SARC-CalF <33, respectively. Surgical menopause was associated with PSO but was not associated with CSSO. Bilateral oophorectomy after menopause and hysterectomy with ovarian preservation were not associated with CSSO or PSO. CONCLUSIONS: In a group of older adult women, the frequency of CSSO was up to 3.0% and PSO up to 2.4%. Surgical menopause was statistically significantly associated with PSO. On the contrary, CSSO was not associated.

Validity and Reliability of the Spanish Version of Fear of COVID-19 Scale in Colombian Physicians.

The Fear COVID-19 Scale (FCV-19S) is a tool that assesses fears related to COVID-19. The objective was to know the validity and reliability of the FCV-19S in Colombian physicians. Five hundred thirty-one physicians aged between 21 and 69 years participated (M = 30.0, SD = 9.4). Internal consistency was estimated with Kuder-Richardson and McDonald's omega coefficients. The one-dimensional structure was corroborated with confirmatory factor analysis and goodness of fit coefficients. The FCV-19S showed Kuder-Richardson's coefficient of 0.16 and McDonald's omega of 0.42. The five-item version (FCV-19S-5), without items 3 and 7, showed Kuder-Richardson's coefficient of 0.67 and McDonald's omega of 0.68. In conclusion, the FCV-19S presented a poor psychometric performance in Colombian doctors, and the FCV-19S-5 showed acceptable internal consistency and dimensionality.

Prevalencia de problemas de sueño en mujeres climatéricas colombianas durante la pandemia COVID-19 / Prevalencia de problemas de sueño en mujeres climatéricas colombianas durante la pandemia COVID-19

Objective: To make an approximation to the prevalence of sleep disorders in Colombian menopausal women during the COVID-19 pandemic Materials and Methods: Cross-sectional study as part of the Quality of Life in Menopause and Colombian Ethnic Groups research project [CAVIMEC+COVID STUDY]. The population consisted of women born and residing in Colombia, 40 to 59 years of age, who signed an informed consent and agreed to participate by completing an online form, freely and anonymously, in the first five days of June 2020. Sleep disorders were identified using the third item on the Menopause Rating Scale. Sociodemographic characteristics, presence and severity of sleep disorders and menopause status were explored. Descriptive statistics are provided. Results: Overall, 984 women aged 47.0 [IQR: 42.0-53.5] years were included: 84.5% mestizo, 13.7% Afro-Colombian, 1.7% indigenous; 39.3% were postmenopausal; 70% lived in the Caribbean region of Colombia. Sleep disorders were reported by 637 women (64.7%), and 112 (11.3%) had severe sleep disorders. Among postmenopausal women, 65.1% reported sleep disorders with 10.1% reporting severe disorders, while 64.5% of premenopausal reported sleep disorders, and 12.2% severe disorders. Conclusions: Sleep disorders could be a frequent problem among premenopausal as well as postmenopausal women in the pandemic time. This issue should be explored during gynecological visits in order to offer solutions. Population studies that confirm these observations are required.

Objetivo: elaborar una aproximación a la prevalencia de los problemas de sueño (PDS) en mujeres climatéricas colombianas durante la pandemia COVID-19. Materiales y Métodos: estudio transversal que pertenece al proyecto de investigación Calidad de Vida en la Menopausia y Etnias Colombianas bajo condiciones de pandemia [CAVIMEC+COVID STUDY]. Se incluyeron mujeres naturales y residentes en Colombia entre 40 y 59 años, quienes en los primeros cinco días de junio del 2020 participaron de forma anónima y voluntaria, previo consentimiento informado en el diligenciamiento de un formulario alojado en una plataforma virtual. Los PDS fueron identificados con el tercer ítem de Menopause Rating Scale. Se exploraron características sociodemográficas, la presencia y severidad de los PDS y el estado menopáusico. Se hace estadística descriptiva. Resultados: participaron 984 mujeres, la mediana de edad fue 47,0 [RIC: 42,0-53,5] años. El 84,5% de las participantes eran mestizas, el 13,7% afrodescendientes y 1,7% indígenas. El 39,3% posmenopáusicas. El 70% residían en la región caribe colombiana. Informaron PDS 637 (64,7%) de las participantes y 112 (11,3%) tenían PDS severos. Las posmenopáusicas informaron un 65,1% de PDS, en forma severa el 10,1%, y las premenopáusicas informaron 64,5%, en forma severa el 12,2%. Conclusiones: los PDS podrían ser un problema frecuente en las mujeres en estado premenopáusico y postmenopáusico. Se debe explorar este problema en la consulta ginecológica para ofrecer soluciones. Se requieren estudios poblacionales que confirmen estas observaciones.

Online assessment of the perception of loneliness and associated factors in Colombian climacteric women during the COVID-19 pandemic: A cross-sectional study.

Background: The coronavirus disease 2019 (COVID-19) pandemic has generated changes due to confinement, this measure can increase the perception of loneliness. The objective was to estimate the frequencies of emotional, social and general loneliness and their association with fear and anxiety with COVID-19, religiosity and severe deterioration of quality of life in middle-aged women. Methods: A cross-sectional study in Colombian women (40-59 y, n=984) surveyed with an electronic form that included sociodemographic characteristics and validated measures (Menopause Rating Scale, de Jong Gierveld Loneliness Scale, fear of COVID-19 scale, Coronavirus Anxiety Scale and Francis Scale for Religiosity). Associations of emotional, social and general loneliness (dependent variables) with severe somatic, psychological, urogenital and quality of life deterioration, as well as with high religiosity, anxiety and high fear of COVID-19 (independent variables), were estimated. Results: The median age was 47 years old, and 39.2% [95% CI: 36.2-42.3] postmenopausal. Severe deterioration in somatic, psychological, urogenital domains and quality of life in women with emotional, social and general loneliness was found (P <0.001). In adjusted models, high fear of COVID-19, severe deterioration of psychological and urogenital domains and quality of life were associated with emotional, social and general loneliness. Anxiety with COVID-19, somatic domain and high religiosity were not associated with loneliness. Conclusion: Emotional, social and general loneliness were identified in 4/10 middle-aged Colombian women surveyed, and the associated factors were high fear of COVID-19, severe deterioration of quality of life and psychological and urogenital domains. Professionals who care for climacteric women should explore the perception of loneliness when assessing menopausal symptoms.

Perceived Loneliness and Severe Sleep Disorders in Adult Women during the Covid-19 Quarantine: A Cross-Sectional Study in Colombia.

BACKGROUND: Quarantine is a measure to control COVID-19 spread, resulting in an increased perception of loneliness. In turn, sleep disorders (SD) may be more frequently reported in uncertain circumstances. OBJECTIVES: To identify the association between loneliness and severe SD, in women quarantined due to the COVID-19 pandemic. METHODS: A cross-sectional study carried out in women, between 40 and 79 years and living in Colombia. The women were invited through social network to complete 5 digital instruments: de Jong Gierveld Loneliness Scale, Menopause Rating Scale, Fear of COVID-19 Five-item Version, Coronavirus Anxiety Scale, and Francis Religion Scale. Bivariate analysis and adjusted logistic regression between loneliness and SD were performed. RESULTS: 1133 women participated, half of them under 50 years old. 43.1% had emotional loneliness, 39.9% social loneliness and 43.3% general loneliness. SD were identified in 6 out of 10 women, those with mild SD presented an OR of 1.84, 1.85, and 1.64, for emotional, social and general loneliness, respectively. Loneliness was associated twice with moderate SD, and more than twice with severe SD. Very severe SD reached OR:5.81 for emotional loneliness, OR:4.38 social loneliness and OR:4.02 general loneliness. In the presence of religiosity, fear and anxiety due to COVID-19, statistical significance was retained for associations, except intense SD with general loneliness. CONCLUSIONS: SD were significantly associated with loneliness in our study population. It is important to assess sleep quality and perception of loneliness in middle-aged women, especially during periods of quarantine due to a pandemic to avoid health implications.

Prevalencia de problemas de sueño en mujeres climatéricas colombianas durante la pandemia COVID-19 / Prevalence of sleep disorders in menopausal women during the COVID-19 pandemic in Colombia

RESUMEN Objetivo: Elaborar una aproximación a la prevalencia de los problemas de sueño (PDS) en mujeres climatéricas colombianas durante la pandemia COVID-19. Materiales y Métodos: Estudio transversal que pertenece al proyecto de investigación Calidad de Vida en la Menopausia y Etnias Colombianas bajo condiciones de pandemia [CAVIMEC+COVID STUDY]. Se incluyeron mujeres naturales y residentes en Colombia entre 40 y 59 años, quienes en los primeros cinco días de junio del 2020 participaron de forma anónima y voluntaria, previo consentimiento informado en el diligenciamiento de un formulario alojado en una plataforma virtual. Los PDS fueron identificados con el tercer ítem de Menopause Rating Scale. Se exploraron características sociodemográficas, la presencia y severidad de los PDS y el estado menopáusico. Se hace estadística descriptiva. Resultados: Participaron 984 mujeres, la mediana de edad fue 47,0 [RIC: 42,0-53,5] años. El 84,5% de las participantes eran mestizas, el 13,7% afrodescendientes y 1,7% indígenas. El 39,3% posmenopáusicas. El 70% residían en la región caribe colombiana. Informaron PDS 637 (64,7%) de las participantes y 112 (11,3%) tenían PDS severos. Las posmenopáusicas informaron un 65,1% de PDS, en forma severa el 10,1%, y las premenopáusicas informaron 64,5%, en forma severa el 12,2%. Conclusiones: Los PDS podrían ser un problema frecuente en las mujeres en estado premenopáusico y postmenopáusico. Se debe explorar este problema en la consulta ginecológica para ofrecer soluciones. Se requieren estudios poblacionales que confirmen estas observaciones.

ABSTRACT Objective: To make an approximation to the prevalence of sleep disorders in Colombian menopausal women during the COVID-19 pandemic. Materials and Methods: Cross-sectional study as part of the Quality of Life in Menopause and Colombian Ethnic Groups research project [CAVIMEC+COVID STUDY]. The population consisted of women born and residing in Colombia, 40 to 59 years of age, who signed an informed consent and agreed to participate by completing an online form, freely and anonymously, in the first five days of June 2020. Sleep disorders were identified using the third item on the Menopause Rating Scale. Sociodemographic characteristics, presence and severity of sleep disorders and menopause status were explored. Descriptive statistics are provided. Results: Overall, 984 women aged 47.0 [IQR: 42.0-53.5] years were included: 84.5% mestizo, 13.7% Afro-Colombian, 1.7% indigenous; 39.3% were postmenopausal; 70% lived in the Caribbean region of Colombia. Sleep disorders were reported by 637 women (64.7%), and 112 (11.3%) had severe sleep disorders. Among postmenopausal women, 65.1% reported sleep disorders with 10.1% reporting severe disorders, while 64.5% of premenopausal reported sleep disorders, and 12.2% severe disorders. Conclusions: Sleep disorders could be a frequent problem among premenopausal as well as postmenopausal women in the pandemic time. This issue should be explored during gynecological visits in order to offer solutions. Population studies that confirm these observations are required.

Somnolencia diurna excesiva identificada con la escala de Epworth en gestantes que acuden a consulta prenatal ambulatoria / Excessive daytime sleepiness identified with the Epworth scale in pregnant women attending an outpatient prenatal consultation

INTRODUCCIÓN: Durante el embarazo se reportan a menudo trastornos del sueño, pero son poco explorados en el control prenatal. El objetivo fue estimar la frecuencia e identificar los factores asociados a somnolencia diurna excesiva (SDE) en gestantes de bajo riesgo obstétrico que acudieron a consulta prenatal. MÉTODO: Estudio transversal dentro del proyecto «Salud biopsicosocial en gestantes», aprobado por el comité de ética de la Clínica Santa Cruz de Bocagrande, Cartagena, Colombia. Se estudiaron mujeres con 12 o más semanas de gestación. Se aplicó un formulario que incluía las escalas de somnolencia diurna de Epworth (ESE), de estrés percibido de 10 ítems (EPP-10) y revisada de depresión del Centro de Estudios Epidemiológicos (CESD-R10). Se realizó regresión logística ajustada y no ajustada de SDE con las otras escalas y variables cualitativas. Se buscó correlación entre variables cuantitativas y la escala de Epworth. Se consideró significativo p < 0,05. RESULTADOS: Se estudiaron 683 mujeres de 28,3 ± 6,3 años y 31,5 ± 6,9 semanas de gestación. Puntuación en la escala de Epworth: 3,82 ± 3,45. En el 4,9% se identificó SDE: 50% leve, 32,2% moderada y 17,6% importante. No se observó en el primer trimestre de gestación y la frecuencia fue similar en los otros; la SDE importante solo se observó en el tercer trimestre. Depresión: odds ratio [OR]: 3,69, intervalo de confianza del 95% [IC95%]:1,83-7,43. Anemia: OR 3,10, IC95%:1,50-6,38. Fatiga: OR 3,22, IC95%:1,23-8,44. Nerviosismo: OR 2,49, IC95%:1,22-5,12. Estrés: OR: 2,38, IC95%:1,12-5,05. Gran paridad: OR: 2,64, IC95%: 1,01-6,89. Trabajar fuera de casa: OR: 2,33, IC95%: 1,05-5,15. Todas estas variables se asociaron con SDE. En el modelo ajustado, la anemia (OR: 3,05, IC95%: 1,44-6,45) y la depresión (OR: 2,72, IC95%: 1,26-5,85) conservaron la asociación. Se observó correlación positiva, despreciable y estadísticamente significativa, de la ESE con la CESD-R10 y con la EPP-10; y ausencia de correlación con la edad materna, la edad gestacional, el número de abortos y el número de cesáreas. CONCLUSIONES: En una de cada 20 gestantes de bajo riesgo obstétrico se identificó SDE, y varias situaciones biopsicosociales se asociaron con mayor presencia.

INTRODUCTION: Sleep disturbances are constantly reported during pregnancy, although they are not often taken care of in prenatal care. The aim was to estimate the regularity and identify factors associated with excessive daytime sleepiness (EDS) in pregnant women at low obstetric risk who attended prenatal consultation. METHOD: Cross-sectional study belonging to the project “Biopsychosocial health in pregnant women”, approved by the ethics committee of the Santa Cruz de Bocagrande Clinic, Cartagena, Colombia. Pregnant women with 12 or more weeks of gestation were studied. A form including: Epworth Daytime Sleepiness Scale, 10-item Perceived Stress and the Revised Depression Scale of the Centre for Epidemiological Studies was applied. Adjusted and unadjusted logistic regression was performed between EDS with the other scales and qualitative variables. In addition, correlation between quantitative variables and the Epworth scale. P<0.05 was significant. RESULTS: 683 pregnant women were studied, maternal age 28.3 ± 6.3 years and gestational age 31.5±6.9 weeks. Epworth Scale score: 3.82 ± 3.45. EDS was identified in 4.9%, 50% mild, 32.2% moderate and 17.6% severe. It was not observed in the first gestational trimester and the frequency was similar in the others, severe EDS only in the third trimester. Depression OR: 3.69 [95% CI: 1.83-7.43], anemia OR: 3.10 [95% CI: 1.50-6.38], fatigue OR: 3.22 [95% CI: 1.23-8.44], nervousness OR: 2.49 [95% CI: 1.22-5.12, stress OR: 2.38 [95% CI: 1.12-5.05], high parity OR: 2.64 [95% CI: 1.01-6.89] and working outside the home OR: 2.33 [95% CI: 1.05-5.15, were associated with EDS. In the adjusted model, anemia OR: 3.05 [95% CI: 1.44-6.45] and depression OR: 2.72 [95% CI: 1.26-5.85] retained the association. CONCLUSIONS: In one out of every twenty low obstetric risk pregnant women EDS was identified and several biopsychosocial situations were associated with more presence.

Resiliencia en gestantes adolescentes del Caribe colombiano: evaluación con la escala de Wagnild y Young / Resilience in pregnant adolescents of the Colombian Caribbean, evaluation with the Wagnild and Young scale

RESUMEN Introducción: las adolescentes presentan cambios biológicos y reciben influencias sociales que las predisponen a quedar embarazadas a temprana edad. Objetivo: evaluar la resiliencia en un grupo de gestante adolescentes para estimar la frecuencia del NRB (nivel de resiliencia bajo) e identificar factores psicosociales asociados. Metodología: estudio transversal en gestantes adolescentes que acudieron a consulta prenatal en Cartagena, Colombia. Se aplicó un cuestionario de características sociodemográficas y es-calas sobre resiliencia, familismo, religiosidad, espiritualidad, funcionalidad familiar, violencia de pareja, felicidad y autoestima. Se compararon dos grupos: NRB y NRAM (nivel de resiliencia alto/moderado). Se realizó una regresión logística multivariada para identificar los factores asociados al NRB. Resultados: se estudiaron 499 gestantes adolescentes con una edad promedio de 17 años. La mitad de ellas pertenecían a familias disfuncionales. Sesenta y cuatro (12,8 %) tuvieron un NRB con factores asociados como bajo familismo OR: 4,736 (IC 95 %: 2,673-8,392), baja autoestima OR: 4,257 (IC 95 %: 1,363-13,295), disfunción familiar OR: 3,902 (IC 95 %: 2,052-7,422), violencia de pareja OR: 2,689 (IC 95 %: 1,082-6,678), deficiente espiritualidad OR: 2,503 (IC 95 %: 1,461-4,287) y reducida felicidad OR: 2,063 (IC 95 %: 1,214-3,506). Conclusión: en una ciudad del Caribe colombiano, en trece de cada cien gestantes adolescentes que acu-den a consulta prenatal, se encontró NRB; disfunción familiar, violencia de pareja en el embarazo, deficien-te perspectiva espiritual, reducida felicidad subjetiva, familismo y nivel de autoestima bajos se observaron asociados.

SUMMARY Introduction: Adolescents present biological changes and receive social influences which predispose them to pregnancies at early age. Objective: To evaluate resilience in a group of pregnant adolescents, to estimate the frequency of low resilience level and identify associated psychosocial factors. Methodoly: Cross-sectional study in pregnant adolescents who went to prenatal visit in Cartagena, Colombia. A sociodemographic characteristics questionnaire and validated scales on resilience, familism, religiosity, spirituality, family functionality, partner violence, happiness and selfesteem were applied. Two groups were compared: high/moderate resilience level (HMRL) and low resilience level (LRL). Multivariable logistic regression was performed to identify factors associated with LRL. Results: 499 pregnant adolescents were studied, average age 17 years, half belonging to dysfunctional families. Sixty four (12,8%) had LRL and were associated factors: low familism OR: 4,736 (IC95%: 2,673-8,392), low self-esteem OR: 4,257 (IC95%: 1,363-13,295), family dysfunction OR: 3,902 (IC95%: 2,052-7,422), partner violence OR:2,689 (IC95%: 1,082-6,678), poor spirituality OR: 2,503 (IC95%: 1,461-4,287) and reduced happiness OR: 2,063 (IC95%: 1,214-3,506). Conclusion: In a city of the Colombian Caribbean, in thirteen of every one hundred pregnant adolescents who attend to prenatal visit, LRL was found. Family dysfunction, partner violence in pregnancy, poor spirituality, reduced subjective happiness, low familism and low level of selfesteem, were associated with LRL.

Psychosocial factors associated with symptoms of generalized anxiety disorder in general practitioners during the COVID-19 pandemic.

Healthcare providers commonly experience symptoms of anxiety during public health crises and pandemics. The objective of the study was to identify the frequency of symptoms of generalized anxiety disorder (GAD) in general practitioners and to estimate the association with particular psychosocial and demographic factors. This is a cross-sectional study, where a total of 531 general practitioners completed an online form that contained sociodemographic variables, questions about fear and perceptions concerning medical work during the COVID-19 pandemic, 7-Item Generalized Anxiety Disorder Scale (GAD-7), questionnaire on psychosomatic problems and Fear of COVID-19 Scale. The presence of symptoms of GAD was defined by a GAD-7 score of 10 or more points. Voluntary and anonymous participation, acceptance of terms, and informed consent were requested. A p value of <0.05 was considered statistically significant. Symptoms of GAD were identified in 4 out of 10 Colombian general practitioners; the following psychosocial and demographic factors were associated with a greater presence of these symptoms: female gender, social discrimination, anguish, job disappointment, nightmares, stress and other symptoms of fear regarding the pandemic. Conversely, feeling protected by the state or employer, being satisfied with their job as a physician, and trusting government measures and information were associated with a lower presence of symptoms of GAD. These findings highlight the importance of timely psychotherapeutic and psychopharmacological interventions in these individuals. The authors suggest mental health providers should be deployed during times of crisis to decrease the risk of developing mental illness.

Pentraxin-3 is a candidate biomarker on the spectrum of severity from pre-eclampsia to HELLP syndrome: GenPE study.

Pentraxin-3 has been reported as a promising biomarker of pre-eclampsia and its severity; however, available studies have small sample sizes, and analyses are not always adjusted for confounders. The aim of this study is to establish the strength of the association between maternal Pentraxin-3 level and pre-eclampsia or HELLP syndrome. It was a case-control study. Women with pre-eclampsia or HELLP syndrome were defined as cases, and women with healthy pregnancies at term (>37 weeks) were classified as controls. Plasma concentrations of Pentraxin-3 were determined at the time of delivery by quantitative enzyme immunoassay. Associations between Pentraxin-3 and pre-eclampsia and HELLP syndrome were assessed by multinomial logistic regression. Subsidiary analysis for the time of disease onset was also carried out. Odds ratios and 95% confidence intervals are reported. A total of 1024 pregnant women were included (461 controls, 368 pre-eclampsia, 195 HELLP). A positive log-linear relationship was found between the top pentraxin-3 quintile and HELLP syndrome. After adjustment for confounders (maternal age, ethnicity, socioeconomic position, date and place of recruitment, family history of pre-eclampsia, smoking, body mass index at beginning of pregnancy, gestational age and multiple pregnancy), the strength of the association was higher for HELLP syndrome [OR 1.13 (95% CI 1.08; 1.18)] than for pre-eclampsia [OR 1.03 (95% CI 1.03; 1.10)]. No difference according to time of onset or pentraxin-3 level was found. In summary, pentraxin-3 level was associated with pre-eclampsia, but it was more strongly associated with HELLP syndrome. Longitudinal studies with a lower probability of residual confounding are necessary to improve our knowledge about the role of pentraxin-3 in pre-eclampsia.

Percepción de discriminación en un grupo de médicos generales colombianos durante la pandemia del COVID-19 y su relación con factores laborales y psicológicos / Perception of discrimination in a group of colombian general practitioners during the COVID-19 pandemic and its relation to labor and psychological factors

RESUMEN Objetivo: Estimar la frecuencia de percepción de discriminación y su asociación con estrés laboral, ansiedad y miedo al COVID-19 en médicos generales colombianos. Métodos: Estudio transversal que perteneciente al proyecto Dinámicas Psicosociales Universitarias, con aval institucional de la Universidad de Cartagena. Un grupo de médicos generales colombianos fue invitado por redes sociales a diligenciar, los primeros cinco días de abril de2020, un formulario de Google Forms© con preguntas sobre miedo y opiniones respecto al COVID-19 con las herramientas Test de Estrés Laboral, Generalized Anxiety Disorder y Fear of COVID-19 Scale. El estudio fue anónimo y voluntario con aceptación de términos y consentimiento informado. Para el análisis de la información se conformaron dos grupos: con percepción de discriminación y sin percepción de discriminación, según respuesta a la pregunta "Haber tenido percepción de discriminación por su condición de médico". Se realizó regresión logística entre percepción de discriminación con ansiedad, estrés laboral y miedo al COVID-19. Resultados: Participaron 531 médicos colombianos, la mitad entre 20-30 años; 207 (39 %) informaron percepción de discriminación. La ansiedad, estrés y miedo relacionados con la pandemia y la labor profesional fueron altamente prevalentes y más frecuentes en el grupo con percepción de discriminación (p<0.05). La presencia y severidad de ansiedad, estrés y miedo al COVID-19 se asociaron con mayor presencia de percepción de discriminación, mientras que sentirse protegido por sus superiores laborales se asoció con menor percepción de discriminación. Conclusión: Dos de cada cinco participantes informaron PPD; fenómeno social que se asoció con ansiedad, estrés y miedo durante la pandemia por COVID-19.

ABSTRACT Objective: To estimate the frequency of perception of discrimination and its association with occupational stress, anxiety and fear of COVID-19 in Colombian general practitioners. Methods: Cross-sectional study that belongs to Dinámicas Psicosociales Universitarias project with institutional endorsement from the Universidad de Cartagena, Colombia. A group of Colombian general practitioners was invited by social networks to fill out, on the first five days of April-2020, a Google Forms © form with questions about fear and opinions regarding COVID-19 with the tools Test of Labor Stress, Generalized Anxiety Disorder and Fear of COVID-19 Scale. The study was anonymous and voluntary with acceptance of terms and informed consent. For the analysis of the information, two groups were formed: with perception of discrimination and without perception of discrimination, according to the answer to the question "Having had perception of discrimination due to their condition as a physician". Logistic regression was performed between perception of discrimination with anxiety, occupational stress and fear of COVID-19. Results: 531 Colombian doctors participated, half between 20-30 years. 207 (39%) reported perceived discrimination. Pandemic-related anxiety, stress and fear and professional work were highly prevalent and more frequent in the group with perceived discrimination (p <0.05). The presence and severity of anxiety, stress and fear of COVID-19 were associated with a greater presence of discrimination perception, while feeling protected by their work superiors was associated with a lower perception of discrimination. Conclusion: Two out of five participants reported perception of discrimination, a social phenomenon that was associated with anxiety, stress and fear during the COVID-19 pandemic.

Ansiedad y depresión identificadas con la Escala de Golberg en estudiantes universitarios del área de la salud / Anxiety and Depression Identified in University Students in the Health-care Field with the Goldberg Scale / Ansiedade e depressão identificadas com a escala goldberg em estudantes universitários da área de saúde

Introducción. Los programas universitarios del área de la salud son exigentes y la rutina es extenuante, por lo tanto, generan estrés y un potencial impacto psicológico negativo en los estudiantes. El objetivo de este estudio fue determinar la prevalencia y los factores asociados a la ansiedad y a la depresión en estudiantes del área de la salud. Metodología. Estudio de tipo transversal aplicado a estudiantes de Medicina, Enfermería y Química Farmacéutica de una universidad colombiana que diligenciaron anónima y voluntariamente un formulario con datos sociodemográficos y, a su vez, la Escala de Ansiedad y Depresión de Goldberg. Se realizó regresión logística: ansiedad o depresión (variable dependiente) y las características sociodemográficas (independientes); p<0.05, estadísticamente significativo. Resultados. Los participantes corresponden a 697 jóvenes, cuyas edades oscilan entre 20.3±1.7. El 43.6% estudiaba Medicina, el 26.2% Química Farmacéutica y el 30.1% Enfermería. Se identificó ansiedad en el 49.8% (intervalo de confianza 95%:46.0-53.4) y depresión en el 80.3% (intervalo de confianza 95%:77.2-83.1). Estudiar Medicina, Enfermería, ser de sexo femenino, padecer de sobrepeso e infrapeso, haber tenido consulta previa psicológica o psiquiátrica, tener medicación permanente y sufrir de alguna enfermedad crónica, se asocia a mayor presencia de ansiedad. Proceder de zonas rurales se asoció a mayor depresión. Discusión. Los hallazgos muestran alta prevalencia de síntomas de ansiedad y depresión en el grupo de jóvenes universitarios del área de la salud. Si bien la escala utilizada no hace diagnóstico, sí sugiere la existencia de manifestaciones patológicas. Factores psicosociales, sobre todo del entorno juvenil, estuvieron asociados. Situaciones similares han sido señaladas por diferentes autores. Conclusiones. Se identificó ansiedad en la mitad de los estudiantes y depresión en ocho de cada diez. Factores inherentes a la vida universitaria, costumbres, hábitos y actividades recreativas se asociaron significativamente. Cómo citar. Monterrosa-Castro A, Ordosgoitia-Parra E, Beltrán-Barrios T, Et al. Ansiedad y depresión identificadas con la Escala de Golberg en estudiantes universitarios del área de la salud. MedUNAB. 2020;23(3):372-388. Doi: doi.org/10.29375/01237047.3881

Introduction. University programs in the health-care field are challenging and their routines are exhausting. Therefore, they create stress and a potential negative psychological impacts on students. This study's objective was to determine the prevalence and factors associated with anxiety and depression in students in the health-care field. Methodology: A cross-sectional study applied to Medical, Nursing and Pharmaceutical Chemistry students from a Colombian university, who anonymously and voluntarily completed a form with sociodemographic data and the Goldberg Anxiety and Depression Scale. Logistic regression was performed: anxiety or depression (dependent variables) and sociodemographic characteristics (independent variables); p < 0.05, statistically significant. Results Six hundred and ninety-seven young adults participated, whose ages ranged between 20.3±1.7. Forty-three point six percent studied Medicine, 26.2% Pharmaceutical Chemistry and 30.1% Nursing. Anxiety was identified in 49.8% (95% confidence interval:46.0-53.4) and depression in 80.3% (95% confidence interval:77.2-83.1). Studying Medicine, Nursing, being female, overweight and underweight, having previously had a psychological or psychiatric consultation, taking permanent medication and suffering from a chronic disease are all associated with a higher presence of anxiety. Being from a rural area was associated with greater depression. Discussion. The findings show a high prevalence of symptoms of anxiety and depression in the group of university students in the health-care field. Even though the scale that was used does not perform diagnoses, it does suggest the existence of pathological manifestations. Psychosocial factors were associated, especially in juvenile environments. Similar situations have been indicated by various authors. Conclusion. Anxiety was identified in half of the students and depression was identified in eight of every ten. Factors inherent to university life, customs, habits and recreational activities were significantly associated. Cómo citar. Monterrosa-Castro A, Ordosgoitia-Parra E, Beltrán-Barrios T, Et al. Ansiedad y depresión identificadas con la Escala de Golberg en estudiantes universitarios del área de la salud. MedUNAB. 2020;23(3):389-404. Doi: doi.org/10.29375/01237047.3881

Introdução. Os programas universitários da área da saúde são exigentes e a rotina é extenuante, gerando estresse e um potencial impacto psicológico negativo nos estudantes. O objetivo deste estudo foi determinar a prevalência e os fatores associados à ansiedade e à depressão em estudantes da área de saúde. Metodologia. Trata-se de um estudo transversal aplicado a estudantes de Medicina, Enfermagem e Química Farmacêutica de uma universidade colombiana que preencheram, de forma anônima e voluntária, um formulário com dados sociodemográficos, assim como a Escala Goldberg de Ansiedade e Depressão. Foi realizada regressão logística: ansiedade ou depressão (variável dependente) e características sociodemográficas (independentes); p<0.05, estatisticamente significativo. Resultados. Os participantes foram 697 jovens, cujas idades variam entre os 20.3±1.7 anos. 43.6% estavam cursando Medicina, 26.2% Química Farmacêutica e 30.1% Enfermagem. Foi identificada ansiedade em 49.8% (IC 95%:46.0-53.4) e a depressão em 80.3% (IC 95%: 77.2-83.1). Estudar Medicina, Enfermagem, ser do sexo feminino, estar com sobrepeso e abaixo do peso, ter feito consulta psicológica ou psiquiátrica anterior, ter medicação permanente e sofrer de alguma doença crônica, são fatores que estão associados a uma maior presença de ansiedade. Vir de áreas rurais foi associado a uma maior depressão. Discussão. Os resultados mostram uma alta prevalência de sintomas de ansiedade e depressão no grupo de jovens universitários da área da saúde. Embora a escala utilizada não faça um diagnóstico, sugere a existência de manifestações patológicas. Fatores psicossociais, especialmente no ambiente juvenil, foram associados. Situações semelhantes têm sido apontadas por diferentes autores. Conclusão. A ansiedade foi identificada em metade dos estudantes e a depressão em oito de cada dez. Fatores inerentes à vida universitária, costumes, hábitos e atividades recreativas foram significativamente associadas. Cómo citar. Monterrosa-Castro A, Ordosgoitia-Parra E, Beltrán-Barrios T, Et al. Ansiedad y depresión identificadas con la Escala de Golberg en estudiantes universitarios del área de la salud. MedUNAB. 2020;23(3):372-388. Doi: doi.org/10.29375/01237047.3881

Anxiety and Depression Identified in University Students in the Health-care Field with the Goldberg Scale / Ansiedad y depresión identificadas con la Escala de Golberg en estudiantes universitarios del área de la salud / Ansiedade e depressão identificadas com a escala goldberg em estudantes universitários da área de saúde

Introduction. University programs in the health-care field are challenging and their routines are exhausting. Therefore, they create stress and a potential negative psychological impacts on students. This study's objective was to determine the prevalence and factors associated with anxiety and depression in students in the health-care field. Methodology: A cross-sectional study applied to Medical, Nursing and Pharmaceutical Chemistry students from a Colombian university, who anonymously and voluntarily completed a form with sociodemographic data and the Goldberg Anxiety and Depression Scale. Logistic regression was performed: anxiety or depression (dependent variables) and sociodemographic characteristics (independent variables); p < 0.05, statistically significant. Results Six hundred and ninety-seven young adults participated, whose ages ranged between 20.3±1.7. Forty-three point six percent studied Medicine, 26.2% Pharmaceutical Chemistry and 30.1% Nursing. Anxiety was identified in 49.8% (95% confidence interval:46.0-53.4) and depression in 80.3% (95% confidence interval:77.2-83.1). Studying Medicine, Nursing, being female, overweight and underweight, having previously had a psychological or psychiatric consultation, taking permanent medication and suffering from a chronic disease are all associated with a higher presence of anxiety. Being from a rural area was associated with greater depression. Discussion. The findings show a high prevalence of symptoms of anxiety and depression in the group of university students in the health-care field. Even though the scale that was used does not perform diagnoses, it does suggest the existence of pathological manifestations. Psychosocial factors were associated, especially in juvenile environments. Similar situations have been indicated by various authors. Conclusion. Anxiety was identified in half of the students and depression was identified in eight of every ten. Factors inherent to university life, customs, habits and recreational activities were significantly associated. Cómo citar. Monterrosa-Castro A, Ordosgoitia-Parra E, Beltrán-Barrios T, Et al. Ansiedad y depresión identificadas con la Escala de Golberg en estudiantes universitarios del área de la salud. MedUNAB. 2020;23(3):389-404. Doi: doi.org/10.29375/01237047.3881

Introducción. Los programas universitarios del área de la salud son exigentes y la rutina es extenuante, por lo tanto, generan estrés y un potencial impacto psicológico negativo en los estudiantes. El objetivo de este estudio fue determinar la prevalencia y los factores asociados a la ansiedad y a la depresión en estudiantes del área de la salud. Metodología. Estudio de tipo transversal aplicado a estudiantes de Medicina, Enfermería y Química Farmacéutica de una universidad colombiana que diligenciaron anónima y voluntariamente un formulario con datos sociodemográficos y, a su vez, la Escala de Ansiedad y Depresión de Goldberg. Se realizó regresión logística: ansiedad o depresión (variable dependiente) y las características sociodemográficas (independientes); p<0.05, estadísticamente significativo. Resultados. Los participantes corresponden a 697 jóvenes, cuyas edades oscilan entre 20.3±1.7. El 43.6% estudiaba Medicina, el 26.2% Química Farmacéutica y el 30.1% Enfermería. Se identificó ansiedad en el 49.8% (intervalo de confianza 95%:46.0-53.4) y depresión en el 80.3% (intervalo de confianza 95%:77.2-83.1). Estudiar Medicina, Enfermería, ser de sexo femenino, padecer de sobrepeso e infrapeso, haber tenido consulta previa psicológica o psiquiátrica, tener medicación permanente y sufrir de alguna enfermedad crónica, se asocia a mayor presencia de ansiedad. Proceder de zonas rurales se asoció a mayor depresión. Discusión. Los hallazgos muestran alta prevalencia de síntomas de ansiedad y depresión en el grupo de jóvenes universitarios del área de la salud. Si bien la escala utilizada no hace diagnóstico, sí sugiere la existencia de manifestaciones patológicas. Factores psicosociales, sobre todo del entorno juvenil, estuvieron asociados. Situaciones similares han sido señaladas por diferentes autores. Conclusiones. Se identificó ansiedad en la mitad de los estudiantes y depresión en ocho de cada diez. Factores inherentes a la vida universitaria, costumbres, hábitos y actividades recreativas se asociaron significativamente. Cómo citar. Monterrosa-Castro A, Ordosgoitia-Parra E, Beltrán-Barrios T, Et al. Ansiedad y depresión identificadas con la Escala de Golberg en estudiantes universitarios del área de la salud. MedUNAB. 2020;23(3):372-388. Doi: doi.org/10.29375/01237047.3881

Introdução. Os programas universitários da área da saúde são exigentes e a rotina é extenuante, gerando estresse e um potencial impacto psicológico negativo nos estudantes. O objetivo deste estudo foi determinar a prevalência e os fatores associados à ansiedade e à depressão em estudantes da área de saúde. Metodologia. Trata-se de um estudo transversal aplicado a estudantes de Medicina, Enfermagem e Química Farmacêutica de uma universidade colombiana que preencheram, de forma anônima e voluntária, um formulário com dados sociodemográficos, assim como a Escala Goldberg de Ansiedade e Depressão. Foi realizada regressão logística: ansiedade ou depressão (variável dependente) e características sociodemográficas (independentes); p<0.05, estatisticamente significativo. Resultados. Os participantes foram 697 jovens, cujas idades variam entre os 20.3±1.7 anos. 43.6% estavam cursando Medicina, 26.2% Química Farmacêutica e 30.1% Enfermagem. Foi identificada ansiedade em 49.8% (IC 95%:46.0-53.4) e a depressão em 80.3% (IC 95%: 77.2-83.1). Estudar Medicina, Enfermagem, ser do sexo feminino, estar com sobrepeso e abaixo do peso, ter feito consulta psicológica ou psiquiátrica anterior, ter medicação permanente e sofrer de alguma doença crônica, são fatores que estão associados a uma maior presença de ansiedade. Vir de áreas rurais foi associado a uma maior depressão. Discussão. Os resultados mostram uma alta prevalência de sintomas de ansiedade e depressão no grupo de jovens universitários da área da saúde. Embora a escala utilizada não faça um diagnóstico, sugere a existência de manifestações patológicas. Fatores psicossociais, especialmente no ambiente juvenil, foram associados. Situações semelhantes têm sido apontadas por diferentes autores. Conclusão. A ansiedade foi identificada em metade dos estudantes e a depressão em oito de cada dez. Fatores inerentes à vida universitária, costumes, hábitos e atividades recreativas foram significativamente associadas. Cómo citar. Monterrosa-Castro A, Ordosgoitia-Parra E, Beltrán-Barrios T, Et al. Ansiedad y depresión identificadas con la Escala de Golberg en estudiantes universitarios del área de la salud. MedUNAB. 2020;23(3):372-388. Doi: doi.org/10.29375/01237047.3881

Estrés laboral, ansiedad y miedo al COVID-19 en médicos generales colombianos / Occupational Stress, Anxiety and Fear of COVID-19 in Colombian Physicians / Estresse ocupacional, ansiedade e medo da COVID-19 em clínicos gerais colombianos

Introducción. Las epidemias pueden generar angustia en la población general y en los profesionales de la salud, y la pandemia causada por el virus del COVID-19 no es a excepción. El objetivo del presente estudio es determinar la presencia de síntomas de estrés laboral, ansiedad y miedo al COVID-19 en médicos generales, además de estimar la asociación según el ente territorial donde trabajaban. Metodología. Este es un estudio transversal que exploró síntomas y percepciones durante la pandemia del COVID-19 en médicos generales colombianos sometidos a cuarentena obligatoria que ejercieron su profesión en marzo del 2020. Previo consentimiento informado, anónima y voluntariamente, los participantes diligenciaron un formulario virtual con preguntas generales sobre COVID-19. El cuestionario buscaba encontrar problemas psicosomáticos sirviéndose de la Escala para el Trastorno de Ansiedad Generalizada (GAD-7, por sus siglas en inglés) y el FCV-19S (Fear of COVID-19). Los participantes se clasificaron en Municipio no capital o Municipio capital, según el ente territorial en donde laboraban. Regresión logística entre el ente territorial (que acá es tomada como variable independiente) con los síntomas de ansiedad, estrés laboral y miedo al COVID-19 (que en este caso es tomado como variable dependiente). Resultados: Participaron 531 médicos generales con edad promedio de 30 años. El 73.3% laboraban en Municipio capital. Un tercio de los encuestados presentó estrés laboral leve, mientras que el 6% presentó estrés laboral alto o severo, esto sin diferencias entre los grupos (p<0.05). Se identificaron síntomas de ansiedad en el 72.9%, más frecuente entre quienes laboraban en las capitales (p=0.044). El 37.1% presentó síntomas de miedo al COVID-19 (FCV-19S). No se observó asociación en la regresión logística realizada. Discusión: Factores psicosociales y psicosomáticos asociados al miedo son el común denominador de los síntomas de ansiedad y estrés laboral en las pandemias. Conclusión: Siete de cada diez participantes presentó síntomas de ansiedad o estrés laboral, mientras que cuatro presentaron síntomas de FCV-19S. No se observó asociación con la clasificación del municipio donde laboraban. Cómo citar. Monterrosa-Castro A, Dávila-Ruiz R, Mejía-Mantilla A, Contreras-Saldarriaga J, Mercado-Lara M, Flores-Monterrosa C. Estrés laboral, ansiedad y miedo al COVID-19 en médicos generales colombianos. MedUNAB. 2020;23(2): 195-213. doi: 10.29375/01237047.3890

Introduction: Epidemics can cause anxiety in the general population and health professionals. The pandemic caused by the COVID-19 virus is no exception. This study's objective is to identify symptoms of work-related stress, anxiety and fear of COVID-19 in physicians, as well as to discover their relation with the territorial body in which they work. Methodology: This is a cross-cutting study that explored the symptoms and perceptions of Colombian physicians forced to quarantine, who exercised their profession in March, 2020 during the COVID-19 pandemic. Having provided informed consent anonymously and voluntarily, participants completed a virtual form with general questions on COVID-19. The survey was aimed at finding psychosomatic problems using the Generalized Anxiety Disorder (GAD-7) scale and Fear of COVID-19 (FCV-19S) scale. Participants were classified as working in non-capital or capital municipalities according to the territorial body in which they practiced. Logistic regression between the territorial body (which was taken as an independent variable here) and symptoms of anxiety, work-related stress and fear of COVID-19 (which, in this case, were taken as dependent variables) was performed. Results: Five hundred and thirty-one general physicians participated, with an average age of 30. Seventy-three point three percent practiced in a capital municipality. One third of the surveyed physicians presented mild work-related stress, while 6% presented high or severe work-related stress, without differences between groups (p < 0.05). Symptoms of anxiety were found in 72.9% of the surveyed physicians, more frequently among those who practiced in capitals (p = 0.044). Thirty-seven point one percent presented symptoms of fear of COVID-19 (FCV-19S). No relation was observed in the logistic regression. Discussion: Psychosocial and psychosomatic factors associated with fear are the common denominators of symptoms of anxiety and work-related stress during pandemics. Conclusion: Seven of every ten participants presented symptoms of anxiety or work-related stress, while four presented symptoms of FCV-19S. No relation was observed with the municipalities in which they worked. Cómo citar. Monterrosa-Castro A, Dávila-Ruiz R, Mejía-Mantilla A, Contreras-Saldarriaga J, Mercado-Lara M, Flores-Monterrosa C. Estrés laboral, ansiedad y miedo al COVID-19 en médicos generales colombianos. MedUNAB. 2020;23(2): 195-213. doi: 10.29375/01237047.3890

Introdução. As epidemias podem causar angústia na população em geral e nos profissionais de saúde, e a pandemia causada pelo vírus COVID-19 não é exceção. O objetivo deste estudo é determinar a presença de sintomas de estresse ocupacional, ansiedade e medo da COVID-19 em clínicos gerais, além de estimar a associação de acordo com a entidade territorial em que trabalhavam. Metodología. Este é um estudo transversal que explorou sintomas e percepções durante a pandemia da COVID-19 em clínicos gerais colombianos submetidos à quarentena obrigatória que exerceram sua profissão em março de 2020. Após consentimento informado, anonimamente e voluntariamente, os participantes preencheram um formulário virtual com perguntas gerais sobre a COVID-19. O questionário procurou encontrar problemas psicossomáticos utilizando a Escala de Desordem de Ansiedade Generalizada (GAD-7, sigla em inglês) e o FCV-19S (Fear of COVID-19). Os participantes foram classificados em município não-capital ou município capital de acordo com a entidade territorial onde trabalhavam. Regressão logística entre a entidade territorial (que aqui é tomada como variável independente) com os sintomas de ansiedade, estresse ocupacional e medo da COVID-19 (que aqui é tomada como variável dependente). Resultados. Participaram 531 médicos de clínica geral com idade média de 30 anos. Do total, 73.3% trabalhavam no município da capital. Um terço dos entrevistados apresentou leve estresse ocupacional, enquanto 6% apresentou estresse ocupacional alto ou severo, isto sem diferenças entre os grupos (p<0,05). Os sintomas de ansiedade foram identificados em 72.9%, mais frequentes entre os que trabalham nas capitais (p=0,044). Ademais, 37.1% tinham sintomas de medo da COVID-19 (FCV-19S). Nenhuma associação foi observada na regressão logística realizada. Discussão. Fatores psicossociais e psicossomáticos associados ao medo são o denominador comum dos sintomas de ansiedade e estresse ocupacional em pandemias. Conclusão. Sete em cada dez participantes apresentavam sintomas de ansiedade ou estresse no trabalho, enquanto quatro apresentavam sintomas do FCV-19S. Nenhuma associação foi observada com a classificação do município onde trabalhavam. Cómo citar. Monterrosa-Castro A, Dávila-Ruiz R, Mejía-Mantilla A, Contreras-Saldarriaga J, Mercado-Lara M, Flores-Monterrosa C. Estrés laboral, ansiedad y miedo al COVID-19 en médicos generales colombianos. MedUNAB. 2020;23(2): 195-213. doi: 10.29375/01237047.3890

Occupational Stress, Anxiety and Fear of COVID-19 in Colombian Physicians / Estrés laboral, ansiedad y miedo al COVID-19 en médicos generales colombianos / Estresse ocupacional, ansiedade e medo da COVID-19 em clínicos gerais colombianos

Introduction: Epidemics can cause anxiety in the general population and health professionals. The pandemic caused by the COVID-19 virus is no exception. This study's objective is to identify symptoms of work-related stress, anxiety and fear of COVID-19 in physicians, as well as to discover their relation with the territorial body in which they work. Methodology: This is a cross-cutting study that explored the symptoms and perceptions of Colombian physicians forced to quarantine, who exercised their profession in March, 2020 during the COVID-19 pandemic. Having provided informed consent anonymously and voluntarily, participants completed a virtual form with general questions on COVID-19. The survey was aimed at finding psychosomatic problems using the Generalized Anxiety Disorder (GAD-7) scale and Fear of COVID-19 (FCV-19S) scale. Participants were classified as working in non-capital or capital municipalities according to the territorial body in which they practiced. Logistic regression between the territorial body (which was taken as an independent variable here) and symptoms of anxiety, work-related stress and fear of COVID-19 (which, in this case, were taken as dependent variables) was performed. Results: Five hundred and thirty-one general physicians participated, with an average age of 30. Seventy-three point three percent practiced in a capital municipality. One third of the surveyed physicians presented mild work-related stress, while 6% presented high or severe work-related stress, without differences between groups (p < 0.05). Symptoms of anxiety were found in 72.9% of the surveyed physicians, more frequently among those who practiced in capitals (p = 0.044). Thirty-seven point one percent presented symptoms of fear of COVID-19 (FCV-19S). No relation was observed in the logistic regression. Discussion: Psychosocial and psychosomatic factors associated with fear are the common denominators of symptoms of anxiety and work-related stress during pandemics. Conclusion: Seven of every ten participants presented symptoms of anxiety or work-related stress, while four presented symptoms of FCV-19S. No relation was observed with the municipalities in which they worked. Cómo citar. Monterrosa-Castro A, Dávila-Ruiz R, Mejía-Mantilla A, Contreras-Saldarriaga J, Mercado-Lara M, Flores-Monterrosa C. Estrés laboral, ansiedad y miedo al COVID-19 en médicos generales colombianos. MedUNAB. 2020;23(2): 195-213. doi: 10.29375/01237047.3890

Introducción. Las epidemias pueden generar angustia en la población general y en los profesionales de la salud, y la pandemia causada por el virus del COVID-19 no es a excepción. El objetivo del presente estudio es determinar la presencia de síntomas de estrés laboral, ansiedad y miedo al COVID-19 en médicos generales, además de estimar la asociación según el ente territorial donde trabajaban. Metodología. Este es un estudio transversal que exploró síntomas y percepciones durante la pandemia del COVID-19 en médicos generales colombianos sometidos a cuarentena obligatoria que ejercieron su profesión en marzo del 2020. Previo consentimiento informado, anónima y voluntariamente, los participantes diligenciaron un formulario virtual con preguntas generales sobre COVID-19. El cuestionario buscaba encontrar problemas psicosomáticos sirviéndose de la Escala para el Trastorno de Ansiedad Generalizada (GAD-7, por sus siglas en inglés) y el FCV-19S (Fear of COVID-19). Los participantes se clasificaron en Municipio no capital o Municipio capital, según el ente territorial en donde laboraban. Regresión logística entre el ente territorial (que acá es tomada como variable independiente) con los síntomas de ansiedad, estrés laboral y miedo al COVID-19 (que en este caso es tomado como variable dependiente). Resultados: Participaron 531 médicos generales con edad promedio de 30 años. El 73.3% laboraban en Municipio capital. Un tercio de los encuestados presentó estrés laboral leve, mientras que el 6% presentó estrés laboral alto o severo, esto sin diferencias entre los grupos (p<0.05). Se identificaron síntomas de ansiedad en el 72.9%, más frecuente entre quienes laboraban en las capitales (p=0.044). El 37.1% presentó síntomas de miedo al COVID-19 (FCV-19S). No se observó asociación en la regresión logística realizada. Discusión: Factores psicosociales y psicosomáticos asociados al miedo son el común denominador de los síntomas de ansiedad y estrés laboral en las pandemias. Conclusión: Siete de cada diez participantes presentó síntomas de ansiedad o estrés laboral, mientras que cuatro presentaron síntomas de FCV-19S. No se observó asociación con la clasificación del municipio donde laboraban. Cómo citar. Monterrosa-Castro A, Dávila-Ruiz R, Mejía-Mantilla A, Contreras-Saldarriaga J, Mercado-Lara M, Flores-Monterrosa C. Estrés laboral, ansiedad y miedo al COVID-19 en médicos generales colombianos. MedUNAB. 2020;23(2): 195-213. doi: 10.29375/01237047.3890

Introdução. As epidemias podem causar angústia na população em geral e nos profissionais de saúde, e a pandemia causada pelo vírus COVID-19 não é exceção. O objetivo deste estudo é determinar a presença de sintomas de estresse ocupacional, ansiedade e medo da COVID-19 em clínicos gerais, além de estimar a associação de acordo com a entidade territorial em que trabalhavam. Metodología. Este é um estudo transversal que explorou sintomas e percepções durante a pandemia da COVID-19 em clínicos gerais colombianos submetidos à quarentena obrigatória que exerceram sua profissão em março de 2020. Após consentimento informado, anonimamente e voluntariamente, os participantes preencheram um formulário virtual com perguntas gerais sobre a COVID-19. O questionário procurou encontrar problemas psicossomáticos utilizando a Escala de Desordem de Ansiedade Generalizada (GAD-7, sigla em inglês) e o FCV-19S (Fear of COVID-19). Os participantes foram classificados em município não-capital ou município capital de acordo com a entidade territorial onde trabalhavam. Regressão logística entre a entidade territorial (que aqui é tomada como variável independente) com os sintomas de ansiedade, estresse ocupacional e medo da COVID-19 (que aqui é tomada como variável dependente). Resultados. Participaram 531 médicos de clínica geral com idade média de 30 anos. Do total, 73.3% trabalhavam no município da capital. Um terço dos entrevistados apresentou leve estresse ocupacional, enquanto 6% apresentou estresse ocupacional alto ou severo, isto sem diferenças entre os grupos (p<0,05). Os sintomas de ansiedade foram identificados em 72.9%, mais frequentes entre os que trabalham nas capitais (p=0,044). Ademais, 37.1% tinham sintomas de medo da COVID-19 (FCV-19S). Nenhuma associação foi observada na regressão logística realizada. Discussão. Fatores psicossociais e psicossomáticos associados ao medo são o denominador comum dos sintomas de ansiedade e estresse ocupacional em pandemias. Conclusão. Sete em cada dez participantes apresentavam sintomas de ansiedade ou estresse no trabalho, enquanto quatro apresentavam sintomas do FCV-19S. Nenhuma associação foi observada com a classificação do município onde trabalhavam. Cómo citar. Monterrosa-Castro A, Dávila-Ruiz R, Mejía-Mantilla A, Contreras-Saldarriaga J, Mercado-Lara M, Flores-Monterrosa C. Estrés laboral, ansiedad y miedo al COVID-19 en médicos generales colombianos. MedUNAB. 2020;23(2): 195-213. doi: 10.29375/01237047.3890

Frecuencia de ansiedad preoperatoria y factores asociados en gestantes programadas a cesárea / Frequency of preoperative anxiety and associated factors in pregnant women scheduled to cesarean section

RESUMEN Objetivo: estimar la frecuencia de la ansiedad preoperatoria (AP) y los factores asociados en las gestantes programadas con cesárea electiva. Metodos: estudio transversal en mujeres con embarazo de término sin actividad uterina ni complicaciones médicas, quirúrgicas u obstétricas, realizado previo a la intervención de cesárea electiva, en Cartagena, Colombia. Participación anónima y voluntaria con consentimiento informado. Se aplicó un formulario de características sociodemográficas y la versión en español de la escala Amsterdam Preoperative Anxiety and Information Scale (APAIS). Se realizó regresión logística no ajustada para observar la asociación de las variables cualitativas con AP, se estimó el coeficiente de correlación entre las puntuaciones de las dos subescalas del APAIS con las variables cuantitativas. Resultados: se estudiaron 326 embarazadas, con edad entre 28,5 ± 6,4 años; 7,9 % adolescentes; 24,2 % primigestantes; 81,9 % con cesárea anterior y 70,8 % sin otras cirugías previamente. El 45 % informó no estar de ningún modo preocupada por la cirugía o anestesia y el 7,8 % quería saber mucho más sobre el procedimiento. La frecuencia de AP y de la necesidad de tener mucha más información de la cirugía o anestesia fue del 9,2 %. El número de familiares en la sala de espera se correlacionó negativamente con AP, rho: -0,127 [IC 95 %: -0,232-0,019]. La necesidad de mucha más información sobre la cirugía o anestesia se asoció con el aumento en la frecuencia de AP, OR: 10,9 [IC 95 %: 4,54-26,36]. También lo fueron los estados civiles: unión libre y separada, con respecto a casada: OR: 3,7[IC 95 %: 1,5- 9,2] y OR: 4,4 [IC 95 %: 1,0-19,3], respectivamente. Conclusión: la frecuencia de AP previa a la cesárea fue de 9,2 %. La necesidad de tener más información sobre la cirugía o anestesia se asoció diez veces mayor la presencia de AP y el número de familiares en la sala de espera se correlacionó negativamente con AP, pero el tamaño del coeficiente de correlación se interpretó como despreciable.

SUMMARY Objective: To estimate frequency of preoperative anxiety (PA) and associated factors in pregnant women scheduled for elective cesarean section. Methods: Cross sectional study in full term pregnant women without uterine activity and without medical, surgical or obstetric complications. Was carried out before elective cesarean section in Cartagena, Colombia. Anonymous and voluntary participation with informed consent. A sociodemographic characteristic form and the Spanish version of the Amsterdam Preoperative Anxiety and Information Scale (APAIS) were applied. Unadjusted logistic regression was performed to observe the association of the qualitative variables with PA and the correlation coefficient between the scores of the two subscales of the APAIS and the quantitative variables was estimated. Results: 326 pregnant women were studied. Age 28, 5±6, 4 years; 7, 9 % teenagers; 24, 2 % primigravid, 81,9 % with previous cesarean section and 70,8 % without other previous surgery. 45, 0 % reported not being in any way worried about surgery/anesthesia and 7, 8 % wanted to know much more about the procedure. The frequency of PA and the need of much more information about surgery/anesthesia was 9, 2 %. The number of relatives in the waiting room was negatively correlated with PA, rho: -0,127[CI 95 %: -0,232 to -0,019]. The need of much more information about surgery/anesthesia was associated with increased frequency of PA, OR: 10, 9 [CI 95 %: 4, 54-26, 36]. Also, civil status was associated: free union and separate respect to married, OR: 3,7[CI 95 %: 1,5-9,2] and OR: 4,4[CI 95 %: 1,0-19,3], respectively. Conclusion: The frequency of PA before cesarean section was 9, 2 %. The need of much more information about surgery/anesthesia, was associated ten times greater presence of PA and the number of relatives in the waiting room was negatively correlated with AP, but the size of the correlation coefficient was interpreted as negligible.